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MRI in research workshop and visitPauline Ali and Matthieu Labriffe
During this MRI workshop, students will have the opportunity to tour the MRI scanner facility, guided by a radiologist specializing in neurological diseases. The session will also include an introduction to brain imaging research, covering key steps such as preprocessing for voxel-based morphometry using automated software, as well as techniques for visualizing brain MRI scans and analyzing results.
Pauline Ali, MD, PhD, is a specialist in Physical and Rehabilitation Medicine with a focus on neurological disorders. Clinically, she works in a rehabilitation unit for brain-injured patients. She completed her PhD in December 2024. Her research investigates motor-cognitive interactions, particularly using dual-task gait as a predictive tool for cognitive decline in patients with mild cognitive impairment. She also completed an international research fellowship with Prof. Manuel Montero Odasso at Western University (Canada), a leader in falls and cognition research.
Bioinformatics workshopSalim Khiati
How to identify precise insights into gene or druf functions using database? Let’s dive into the NCI60, GTEx Portal, and CCLE databases to gain a sense of this approach.
Following his PhD in biochemistry at the University of Bordeaux II, Salim Khiati worked 3 years as postdoctoral fellowship at the NIH in Bethesda, USA. In 2015, he joined the MitoLab team within the MitoVasc lab in Angers. Currently, as an assistant professor, his research centers on deciphering the functions of mitochondrial genes, particularly mitochondrial cancer-testis antigens (mitoCTAs), utilizing a combination of bioinformatics and experimental approaches (PMID: 34056600, PMID: 33220498, PMID: 35189384).
Cell imaging experimentsArnaud Chevrollier
Participants will visit the imaging platform to explore various technological approaches, including electron microscopy, confocal microscopy, and super-resolution (SR). They will also take part in an experimental application involving fluorescent labeling of neuronal cells and SR-dSTORM acquisition.
Arnaud Chevrollier is a professor in biochemistry and bioinformatics at the Technological Institute in Medical Bio-engineering of the University of Angers. He is a research member of MitoVasc laboratory. He dedicated 20 years of research on physiopathological evaluation of mitochondrial rare diseases related to mitochondrial dynamics, by focusing on mitochondrial structure function relationships. He implemented and performed fluorescent super resolution microscopy in Angers. Arnaud Chevrollier is in charge of the SCIAM microscopy facility.
Anatomy virtual immersionFlorian Bernard
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This workshop will offer an interactive and innovative approach of neuroanatomy. Students will have the opportunity to study the central nervous system using the AKIVI platform. This interactive class will link fundamental morphological anatomy with its clinical applications.
Dr Florian Bernard is a neurosurgeon specialized in skull base surgery and vascular neurosurgery. He also holds a PhD in functional anatomy and virtual reality, and is a researcher within the CRCINA (INSERM U1232). Dr Florian Bernard is deeply involved in innovative teaching at the University of Angers. He created AKIVI (Anatomical Knowledge In Virtual immersion), an application for studying anatomy.
